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Sep 11, 2010  |   Sep 12, 2010   

Hour
Name
Title

8:00 - 8:45 am
Breakfast

8:45 - 9:00 am
(Cohen/Batchinsky)
Welcome and Introductory Remarks
9:00 am - 12:00 pm
Unraveling fundamental laws in Biology: Dynamic models and biological interactions during acute illness
Moderator: Tim Buchman
Panelist: Benjamin Mann, Ary Goldberger,
     Chris Macedonia, Atul Butte

9:00 - 9:25 am
Benjamin Mann
On Dirac limits and a new point of view on Mathematical Biology

9:25 - 9:50 am
Chris Macedonia
Biochronicity

9:50 - 10:15 am
Ary Goldberger
The Breakdown of Spatio-Temporal Complexity in Acute Illness: Toward Dynamical Biomarkers in the ICU

10:15 - 10:40 am
Michael W. Deem
Spontaneous Emergence of Modularity as a Law in Biology

10:40- 11:05 am
Patrick Norris
From Data Capture to Decision Support: The Past, Present, and Future of SIMON

11:05- 12: pm
Moderator and Experts
Questions and Free discussion

12:00 - 1:00 pm
Lunch
1:00 pm - 3:30 pm
Monitoring Biological Control and Regulation
Moderator: John Karemaker
Panelist: Bruce West; Dwain Eckberg; Tom Kuusela,
     John Doyle

1:00- 1:20 pm
John Karemaker
Overview of the cardiovascular regulatory system. Blood pressure variability

1:20- 1:40 pm
Dwain Eckberg
Measuring cardiovascular regulation using heart rate variability analysis: what it is and what it is not.

1:40- 2:00 pm
Bruce West
(?)
Semantics of complexity: implications for understanding control in physiology

2:00- 2:20 pm
Tom Kuusela
Measuring cardiovascular control using tools from nonlinear dynamics: from physics to physiology and back.

2:20- 2:40 pm
Ted Dick, Rishi Dhingra, Frank Jacono, Christopher G. Wilson, Kenneth A. Loparo, Mikkel Fishman and Ilya Rybak (Drexel University):
Breathing Pattern Variability: Neural Mechanisms & Modeling.

2:40- 3:00 pm
John Doyle
Cardiovascular control and regulation: from mathematics to physiology and back.

3:00- 3:30 pm
Moderator and Experts
Questions and Free discussions. (Refreshments)
3:30 pm - 6:00 pm
Invited Overview Talk: Modeling methods and tools
Moderator: Gary An
Panelist: Ioannis Androulakis, Scott Diamond, Eberhard Voit, Yoram Vodovotz.

3:30- 3:50 pm
Gary An
Characterization of fundamental aspects of biology with abstract mathematics: Category Theory as a pathway for dynamic computational modeling of biological systems

3:50- 4:10 pm
Ioannis Androulakis
Towards a Mechanistic Understanding of Inflammation and Physiologic Variability

4:10- 4:30 pm
Scott Diamond
Novel Methods and Approaches to Modeling Coagulation

4:30- 4:50 pm
Eberhard Voit , Weiwei Yin
Systems Analysis of the Role of Bone Morphogenic Protein 4 in Endothelial Inflammation

4:50- 5:10 pm
Yoram Vodovotz
Computational Models of Inflammation: Translational Applications to Acute Illness

5:10- 6:00 pm
Moderator and Experts
Questions and Free discussions. (Refreshments)
6:00 - 7:00 pm
(Dinner at posters) Expert review of posters.
Chairs: Gilles Clermont, Sven Zenker